Electrostatic potential surface for M153
This anaesthetic has a single low-energy conformer.
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Surface view shows the electrostatic potential of the structure mapped onto the solvent excluded surface, based on a probe of radius 1.4Å. Regions of negative potential are shown in red, positive in blue.
 
Structure Details
Structural Formula SF6
Molecular Formula F6S
Chemical Group Other
Anaesthetic Type Inhalational: Conventional Agent
Chiral Structure No
molfield.org ID M153
CAS Number 2551-62-4
ChEMBL (External Link) CHEMBL1796998
ChEBI (External Link) CHEBI:30496
Drug Bank (External Link) -
ChemSpider (External Link) 16425
PubChem (External Link) 17358
Chemicalize.org (External Link) CAS No 2551-62-4
SMILES String FS(F)(F)(F)(F)F
Molecular Weight (g.mol-1) 146.06
In Vivo Activity Data
Immobility: MAC Rat (atm)14.6 ± 1.3 (n=10)Koblin DD, Fang Z, Eger EI II, et al. Anesth Analg 1998;87:419-24
Immobility: MAC Dog (atm)4.9 ± 0.4 (n=5)Eger EI II, Lundgren C, Miller SL & Stevens WC. Anesthesiology 1969;30:129-35
Physical Properties
Olive Oil / Gas Partition Coeff. at 37°C0.26Koblin DD, Fang Z, Eger EI II, et al. Anesth Analg 1998;87:419-24
Calculated Molecular Properties
van der Waals Volume 68 Å3 
van der Waals Surface Area 97 Å2 
Solvent Accessible Volume 282 Å3(based on a 1.4Å probe)
Solvent Accessible Surface Area 217 Å2(based on a 1.4Å probe)
All values are mean ± SD, except data labelled with † which are mean ± SEM. Use of this web site assumes acceptance of our Copyright & Licence conditions.
Database Version: 1.09.9     Last Updated: 21st February 2014